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For example, the sale of generic drugs in Canada represented over 40 percent of prescription pharmaceuticals by volume, but just under 14 percent of sales by value In other words, 60 percent of pharmaceuticals by volume account for 86 percent of the money spent on prescription drugs in Canada In the United States, the dollar value of branded pharmaceuticals in creased over 85 percent from 1997 to 2002, whereas the dollar value of generics sold during the same period increased 68 percent Despite projec tions of increased volume of generics in order to cut costs, the dollar value spent on branded prescription pharmaceuticals is likely to escalate Stan dard & Poor s estimates that continued growth of spending on branded prescription drugs in the United States will be at the single digit level through 2005.

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When the application is built, the code in the le for the class and the les for any partial classes are combined into one logical class So the runtime behaves as if there is only one class One other bene t of partial classes is the ability to separately de ne Option Strict Your primary class can have Option Strict set to On, and your partial class can have Option Strict set to Off This is useful if you have code that needs to work with objects without concern for conversion of their types, such as when calling components written in VB6 or other Component Object Model (COM)-based technologies Don t use partial classes unnecessarily Dividing a class into multiple class les for no particular purpose makes it more dif cult to maintain the class It is more dif cult to nd where code resides and see how it interacts with other code in the class Use partial classes for the de ned purpose separating generated code from custom code If you are not writing your own code generators, you may never need to create a partial class If you use third-party code generators, you may notice the partial classes that they create

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+ (f(x,y)

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A single class le can contain any number of classes Although you normally de ne a class within its own class le, you can add support classes for that class directly in the same class le For example, say you de ne a ProductOutOfStockException class that is used only by the Product class You can de ne this exception class in the same code le as the Product class:

(6.1.48)

To appreciate the effect of patent protection and the related legal ma neuvering on bolstering sales of branded pharmaceuticals (and elevating the cost of medical care) consider that in the year prior to the expiration of AstraZeneca s US patent on Prilosec, sales in the United States were in excess of $4 billion However, in spite of legal maneuvering by As traZeneca to block equivalent generic drugs, lower-cost generics appeared on the market in 2002 By 2003 sales of Prilosec in the United States were.

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End Class ' End of the Product Class <Serializable()> _ Public Class ProductOutOfStockException Inherits ApplicationException Public Sub New(ByVal message As String) MyBaseNew(message) End Sub

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Expiration 2001 2002 2003 Brand Prilosec Prozac Claritin Reglan Cipro Singulair Flovent Accupril Di ucan Inspra Prevacid Zocor Zoloft Pravachol Glynase Paxil Novantrone Pulmicort Elocon Plendil Fempatch Zemuron Aciphex Skelid Cozaar Vivelle Azopt Eloxatin Frova Nizoral AD Novolog Nexium Alphagan Mylotarg Caverject Elidel Gabitril Geodon Covera-HS Nasonex Zemplar Nuvaring Sustiva Ultram Lexcol XL Generic

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