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Placed in this category are neuropathies that evolve over several weeks to months and, after reaching their peak of severity, tend to persist for a variable period Admittedly, the dividing line between such cases and those that evolve over somewhat shorter or longer periods is indistinct; there are diseases of nerve that overlap both the acute and the early chronic categories In contrast to the acute polyneuropathies, however, most of those that are subacute have prominent sensory features and are of axonal type The exception is a subacute in ammatory-demyelinative type, essentially a slow form of GBS, evolving over 4 to 8 weeks as described by Hughes and coworkers Similarly, some instances of diphtheritic neuropathy evolve subacutely Despite these quali cations, in the end, a symmetrical polyneuropathy syndrome of subacute type most often proves to be due to alcoholism and nutritional de ciency, to a remote effect of cancer (paraneoplastic, as described later), or to poisoning with arsenic, lead, or to the toxic effects of any number of drugs used for therapeutic purposes (cisplatin, nitrofurantoin, isoniazid, etc) Occasionally other drugs, metals, and industrial solvents are incriminated; these are discussed in Chap 43 free 2d barcode generator excel PDF417 Native Excel Barcode Generator - Free download and ...
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